What’s the difference between E 350 and E 450 Mercedes?

May 16th, 2022 by

What’s the difference between E 350 and E 450 Mercedes?

Mercedes-Benz’s E-Class vehicles offer power and performance in a stylish, technologically advanced package. If you’re looking to own the road in comfort and luxury, check out this popular sedan. But before you drive off the lot, consider the different E-Class models Mercedes-Benz offers. While the E 350 and E 450 are very similar, there are some key differences to consider. At Mercedes-Benz of Fairfield, we want you to find a ride that matches all your preferences. Read on to learn more about the Mercedes-Benz E-Class E 350 and E 450 models and compare and contrast these great options. If you have any questions, give us a call at (707) 430-0101.

mercedes e-class in fairfield, ca


One of the biggest differences between the E 350 and E 450 E-Class models is the sources of their power. In the E 350, you can enjoy a turbocharged four-cylinder engine that creates 255 horsepower and 273 lb-ft. of torque. The E 450 comes with a turbocharged inline-six-cylinder engine with a 48-volt hybrid system that you can use as an electric supercharger. Together, this E 450 engine creates an impressive 362 horsepower and 369 lb-ft. of torque. Although both engine options are impressive, if you’re really looking to supercharge your ride, the E 450 has you covered.


On all E-Class models, you can enjoy a high-performing nine-speed automatic transmission. The E 350 comes in a rear or all-wheel drive option while the E 450 comes standard with all-wheel drive. Mercedes-Benz’s 4MATIC® all-wheel-drive system provides improved traction and control in all driving conditions. Consider this option for your most adventurous drives.

Both options drive comfortably. To enhance your driving experience, you can select an optional air suspension add on for a smooth and capable ride. Additionally, a sports brake system provides increased control on the road and is available for the E 350 and standard on the E 450.

Fuel Economy

With the E 350, you can expect an estimated 22 mpg in the city and 31 on the highway with the rear-wheel-drive option and 22 mpg in the city and 30 mpg on the highway in all-wheel drive. While the E 450 is more powerful, it offers comparable mileage. You’ll get an estimated 23 mpg in the city and 30 mpg on the highway with your hybrid infused engine.

Exterior Features

All E-Class models come standard with the Mercedes-Benz’s classic, luxury look. These iconic vehicles demand attention on the road with smooth, clean lines and intelligent accents. Across all models, you can enjoy an expansive list of color options, including Nautical Blue metallic, Starling Blue metallic, and Manufacktur Moonlight White. Standard features across models include stylish and functional automatic high-beam headlights. You can also add an optional hands-free liftgate option to all models.

With the E 350, you can enjoy an optional AMG® Line Exterior w/Night Package that comes with features like gloss black exterior accents, 18-inch AMG® 5-spoke wheels with black accents, and the sport brake system that comes standard on the E 450. The E 450 model offers a similar Night Package that provides the same black accents and wheels. If you’re looking for a breathtakingly beautiful ride, both the E 350 and E 450 should turn heads.

Interior Features

The E-Class’s luxury doesn’t stop once you get inside the vehicle. You can enjoy features like brushed aluminum, wood paneling, comfortable seating, and climate control across models. Optional features for both models include cooled and heated front seats, massaging front seats, a panoramic sunroof, ventilated front-seat cushions, and a heads-up display. Across models, you can enjoy impressive storage space for a five-passenger ride thanks to the lowering rear seatbacks. The E-Class models are built to take you and your passengers wherever you need to go in comfort and style.

For interior tech, you’ll get a 12.3-inch touchscreen infotainment system. You can control this innovative system using a touchpad in the vehicle’s center console or with voice-activated commands. Your system comes standard with Apple CarPlay and Android Auto. Across models, you can upgrade to a Burmester stereo, SiriusXM 6-month Platinum Plan trial, and wireless charging system to really lean in on your ride’s luxury offerings. For added convenience, both models come with a standard universal garage door opener and remote trunk release.

For your coldest winter drives, both models offer a warmth and comfort package that adds a rapid heating feature for your front seats, heated armrests, and a heated steering wheel to truly surround you with warmth. No matter what condition you drive your E-Class in, you should stay comfortable with these standard and optional features. You’ll love what the E-Class has in store.


Mercedes Benz’s E-Class vehicles all offer plenty of standard and available features to keep you safe on the road. Standard features across models include automated emergency braking and blind-spot monitoring. You can also enjoy a standard backup camera, tire pressure monitor, brake assist, and stability and traction control.

Available add-ons come in the form of some great optional packages. The driver assist package includes great features like distance assist, steering assist, evasive steering assist, blind spot assist, lane-keeping, lane change assist, brake assist with a cross-traffic function, congestion emergency braking, emergency stop assist, route-based speed adaption, and extended restart in stop-and-go traffic. With the available premium package, you can enjoy a surround-view system and rear cross-traffic alert. No matter which E-Class option you choose, you have the option to customize your ride to your exact specifications.

Come stop in our local Fairfield showroom to explore other exciting features today. You can also check out our extensive collection of new vehicles and explore our pre-owned options. If you’re ready to commit to an E-Class option that meets your preferences for interior luxury, you can learn more about the online buying process today.

At your Mercedes-Benz of Fairfield, we want you to select the exact vehicle that makes sense for you and your lifestyle. While both the E 350 and E 450 models are great options, there are some key differences that can influence your decision. If you have any questions about these models and their features, you can always contact us today. We can’t wait to meet you and to help you drive off in your dream Mercedes-Benz vehicle.


Posted in E Class